G e r m a n  /  R u s s i a n     V i r t u a l     N e t w o r k     o f     B i o i n f o r m a t i c s  " C o m p u t a t i o n a l   S y s t e m s   B i o l o g y "


  • Scope

  • History

  • Institutions involved

  • Members

  • Events

  • Financial support opportunities (grants)

  • Financial network support

  • Links

  • Contacts

  • Distance education & e-learning

    Novosibirsk State University, Chair of Informational Biology

    Selected courses (content, sample slides, etc.).

    Computational Systems Biology

    1. Genomic Regulatory Signals (example slides)

      • Mechanisms of transcriptional control

      • The databases on transcriptional regulation

      • Conformational and physicochemical context-dependent DNA properties used for functional sites recognition and analysis. B-DNA Video Internet system.

      • Gene expression control on the mRNA translation stage

      • The recognition of promoters

      • Analysis and recognition of transcription factor binding sites

    2. Computational Genomics (example slides)

      • Internet-resources for DNA sequence search and analysis

      • General subject of bioinformatics

      • Databases on Genes and Genomes

      • Repeats in DNA, formal description and analysis

      • Consensus, position weight matrices, sequence alignment methods

      • Machine learning methods overview: hidden Markov models, neural networks, genetic algorithm

      • Methods for eukaryotic gene structure annotation

      • Statistical approaches used for different recognition techniques: accuracy comparison

      • Investigation of qualitative and quantitative characteristics of transcriptome

    3. Gene networks (example slides)

      • Reconstruction gene network and analysis of their properties

      • The arhitecture of gene network

      • Apoptosis gene network

      • The development networks

      • Gene network complexity of prokaryotes and eukaryotes

      • The principle of organization of metabolic networks

      G e r m a n  /  R u s s i a n     V i r t u a l     N e t w o r k     o f     B i o i n f o r m a t i c s