Institute Cytology and Genetics

Laboratory of Cell Biology

Head A.G.Blinov, Ph.D.

Phylogenetic tree of species of the Chironomus genus derived from the ssp 160 sequences

The structural organization of C.thummi non-LTR retrotransposon Nltr1Cth

Research is conducted by two groups at the Laboratory. The group of cytologists is mainly concerned with karyotype structure, chromosome evolution in chironomids, and cytogenetic analysis of natural chromosome populations in Holarctic. The role of chromosome rearrangements was studied by comparative analysis of banding patterns in polytene chromosomes of 81 species of 11 genera of Chironomini (Diptera, Chironomidae) of the Chironomini tribe. It was demonstrated that karyotype divergence is based on the fixation of chromosome rearrangements of different kinds.

Primary research interests of the group of molecular biology are molecular phylogeny of the Chironomus genus, the structure and distribution of transposable elements in different organisms, including the model Caenorabditis elegans.

Phylogenetic relationships among 52 chironomus species, members of 5 different genera of the Chironomidae family, were deduced from comparative analysis of partial nucleotide sequences of the nuclear and mitochondrial genes. The built phylogenetic trees reflect the relationships among.

Timely themes of recent research are the mechanisms that regulate the expression of non-LTR retrotransposons exemplified by C. elegans Rte-1 elements.