8. Sector of Virology.
(1) Staff:
- Nina L. Galachar, Ph.D., Head of the Sector
- Elena G. Ufimtseva
(2) Subject of research:
- The problem of gene determined resistance to retroviruses on the model of avian AMV-infection.
- Interspecific hybridomas.
(3) General Result 1993-1995:
The resistivity mechanisms to retroviral AMV-infection and
the leucogenesis for high resistive and low resistive lines of
avians are investigated.
(4) Publication:
- Galachar N.L. (1993). The resistance to AMV-infection for
different genetic lines of chicken with different degree of virus
induced acute AMV-leukosis. In: Collected articles. Ufa, pp.88-92.
- Galachar N.L. (1994). The natural resistance factors of
chicken lines high-and low resistant to AMV-virus. In: Collected
articles. N 2. Novosibirsk.
- Patent N 1641885 "The stock of mice Mus musculus and mink Mustella
vison interspecific hybridomas cultivated producent of the monoclonal
mink immunoglobulin". June 16, 1993. Russia.
(5) Participation in State and International Programs:
The state program of Russia "The physico-chemical fundamentals of
biology and evolution of natural systems, problems of genetics and
selection, physiology of plants and biotechnology".
(6) Subject of Scientific Collaboration:
- The collaboration with Institute of cancer, Heidelberg,
Germany.
- The collaboration possible in the field of viral oncology on
the models used by authors and on their models as well.
- Further research is necessary of the mechanisms, that provide the
resistance to retroviral infections, to oncoprocesses development
induced by that viruses, and, at last, of mechanisms, that are the
basis for regression of oncoprocess observed for sane individuals.
- The collaboration with Laboratory of heterohybridomas, Surray
University, UK.
- We should like to collaborate in investigations on interspecific
hybridomas, in particular, in investigations on Ig genes expression.